careful and sensible; showing good judgement (Oxford)
having or showing reason and good judgment in making decisions (Cambridge)
It is curable with judicious use of antibiotics. (Oxford)
Some dishes would be very bland without the judicious use of spices and other seasonings. (Oxford)
We should make judicious use of the resources available to us. (Cambridge)
judicious use of antibiotics
judicious use of spices
judicious use of the resources
Careful
Sensible
Careless
Reckless
Judiciously